Projects
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Trial-Ready Cohort – Down Syndrome (TRC-DS)
The purpose of the TRC-DS project is to create a group or ‘cohort’ of adults with Down syndrome who are interested in participating in clinical trials aimed at discovering treatments that will reduce the risk of developing Alzheimer’s dementia. TRC-DS will help researchers enroll participants into these trials quickly to allow new treatments to be discovered as soon as possible. TRC-DS is an observational study being coordinated by the University of Southern California Alzheimer’s Therapeutic Research Institute (USC ATRI) and conducted across more than 15 international sites.
If you or someone you know may be interested in participating in TRC-DS, please visit the website at https://www.trcds.org/. The website is a great place to find more details about the study, including how to join, FAQs, and site locations.
ABATE Study: Join the fight against Alzheimer’s disease
People with Down syndrome often get Alzheimer’s disease (a type of dementia) when they get older. Dementia is a disease that causes memory loss and other thinking problems. Dementia due to Alzheimer’s occurs when a protein called amyloid builds up in the brain.
ABATE is an interventional study sponsored by AC Immune SA, a Swiss-based pharmaceutical company developing new treatments for neurodegenerative diseases, including Alzheimer’s disease. The study is testing a vaccine for Alzheimer’s disease in people with Down syndrome. The trial is being conducted by AC Immune in collaboration with the NIH-funded Alzheimer’s Clinical Trials Consortium – Down syndrome (ACTC-DS).
About 80 people with Down syndrome between 35 and 50 years old will take part in the ABATE study across 15 international sites in the US, the UK, and Spain.
If you or someone you know are interested and would like to learn more about the study, please visit www.Abate-study.com. You will find more information including the location and contact details of your nearest research center.
