People

Jason Karlawish, MD

Perelman School of Medicine, University of Pennsylvania, Penn Memory Center

Jason Karlawish is a Professor of Medicine, Medical Ethics and Health Policy, and Neurology at Penn and cares for patients at the Penn Memory Center (www.pennmemorycenter.org), which he co-directs. He leads the ACTC Ethics Committee, is a member of the Recruitment and Retention Core and the Steering Committee. At Penn, he leads the Outreach and Recruitment Core and Research Education Component of the ADRC. His research focuses on issues at the intersections of bioethics, aging and the neurosciences. He leads the Penn Program for Precision Medicine for the Brain (P3MB). P3MB developed standards for Alzheimer’s disease biomarker disclosure and investigates the clinical impacts of this knowledge on persons and their families. He has investigated the development and translation of Alzheimer’s disease treatments and biomarker-based diagnostics, informed consent, quality of life, research and treatment decision making, and voting by persons with cognitive impairment and residents of long term care facilities.  P3MB developed the amyloid imaging disclosure process and the SOKRATES Study, originally used in the A4 Study, these have become a template for assuring the safe disclosure of Alzheimer’s disease genes and biomarkers and assessing their impact on persons and their families.